Dr. Sharman's CLL & Lymphoma Blog

NEWSFLASH: Resonate-2, the randomized phase III study comparing frontline ibrutinib against chlorambucil met its primary endpoint of progr...

When we are investigating new drugs that have never been tested before, we start with what's called a phase 1 study.  Historically, the ...

When a B cell (either CLL or NHL) signals through the b cell receptor - a sequence of enzymes gets activated.  This starts with Syk, goes to...